Well... count me in as one of those people who isn't too clear on how DNA "works" (although I don't watch shows like Law and Order or CSI). :lol
To be honest, I liked the film! It is a "gorgeous" movie (especially the "map of the universe" sequence). And as I said, Fassbender's performance was outstanding.
I tend to watch movies that I like dozens of times absorbing details I may have overlooked, misinterpreted, or forgotten. However I've only watched Prometheus a few times so far.
The biggest problem I have to overcome is how this "fits" into the timeline of the Alien universe (God I hope I'm not providing fodder for more pointless bickering :lol :rolleyes).
The Prometheus seems much more advanced than the Nostromo or even Sulaco yet it predates them by several decades. It also has all this neat hardware such as the "auto-doctor" (for lack of the correct term). Would have been great to have that toy aboard the Nostromo.
However I have to appreciate that the Prometheus is owned by a billionare and is not a commercial towing vessel nor a military warship (neither of which would have any luxuries). So despite it seeming out of place technology wise, I have to think of it more like a cruise ship (even though it is a research vessel) and not a transport truck or aircraft carrier.
For me the one thing that makes or breaks the Alien franchise is the human characters. "Jaws" is about a shark, "Alien" is about... an alien

lol) however if they had wooden, one dimensional characters with lackluster acting performances neither film would be more tnan a B-movie horror flick with some decent jump scares.
My problem with Prometheus is that the one character I have the most genuine interest in happens to be an android!
Shaw was no Ripley for me. I can't really discuss this in anymore detail without dancing over the TOS.
Captain Janek seemed like they were trying for some cross between Parker and Sergeant Apone. The charisma seemed forced.
Holloway... just not likable. While his death scene was well acted, I just didn't "feel" for him. Certainly not in the same way that I was sorry to see Dallas, Apone, or Drake bite the bullet.
I "didn't" like Theron's character however I guess that is good because I'm supposed to dislike her (I wouldn't go so far as say hate though). However her death just had me thinking "You
dummy!" :rolleyes
Peter Weyland's best bit was the deleted scene!
The rest of the cast were useless. A completely unlikable geologist who gets "lost" despite having all these fancy tracking/mapping devices. A biologist scared of a 2000 year old corpse
et al.
I cared about the crew of the Nostromo. I cared about the Marines of the Sulaco. And to a degree was even able to have some feeling for the main characters of Fury 161. However I just couldn't feel anything for the crew of the Prometheus.
Hopefully the film will grow on me with more viewings. I don't hate it by any stretch.
Kevin