The house is has been used a lot over the decades.
First used the Ennis house as a film location in 1933 for the film:
Female.
The house provided the exterior facade for the
House on Haunted Hill, in 1959.
In 1975 film The film:
The Day of the Locust made extensive use of the house.
And of course in 1982
Bladerunner.
Its exterior also appears as "The Mansion" occupied by Angelus, Spike, and Drusilla in the television series
Buffy the Vampire Slayer.
Sections of the cathedral reminiscent interior, especially the elevated dining room and fireplace, have appeared in over a dozen films including
The Karate Kid Part III revealing the view of downtown Los Angeles,
Black Rain,
The Glimmer Man,
The Replacement Killers,
Rush Hour substituting for a floor of a Hong Kong skyscraper, and
The Thirteenth Floor.
The house has also been used as a location for
commercials, fashion magazine shoots and music videos, including
3T's "Why" featuring Michael Jackson. S Club 7's video for the single "Have You Ever" shows the band members living an everyday life in the house and Ricky Martin music video song "Vuelve".
And as stated, a few films like Predator 2 have used sets "inspired" by the Ennis house:
(From Wikipedia)
"Fillmmakers either recreated original elements of the Ennis House on sound stage sets or vaguely imitated these as in
Predator 2 and several
episodes of Star Trek: The Next Generation. After shooting the exterior scene on location for Blade Runner,
the interior of Deckard's apartment was created at Warner Brothers.
In the case of The Rocketeer, sections of the Ennis House were recreated in detail, including the patterned art glass, on a studio set. The Rocketeer went as far as adding an upper floor. On a smaller scale, tile casts of the block relief ornamentation were used for the Club Silencio doorframe in Mulholland Drive.
David Lynch also used Ennis House for a
few segments of the show Twin Peaks in which the soap opera show-within-a-show called Invitation to Love was all shot in Ennis House."