Actually, when mixing leds in a circuit physical size is irrelevant. The factors to watch out for are a. maximum current capacity and b. led color. (It is not necessary to run leds at maximum current. In fact, if your power supply is limited running leds at reduced current is a good thing.) The voltage across leds is determined by color. Blue, green, and white leds need 3.5 volts to light up. Red and yellow need 1.75 volts. Take this into consideration when calculating the current limiting resistor. When running leds in series add up the led voltages and use that to choose the resistor (you only need one resistor per led or string of leds). Running leds in series does not have the reliability issues that you get with light bulbs in series.