I'm a Sketchup user, for the simple reason that it does what I need, is free, and has a ton of Ruby plug-ins available to it for free that will allow it to do most everything the others can. It may take some work to get used to its interface if you've used any other program though. Its leaning curve is VERY easy, unlike Blender, IMO. I've found that the programs out there that were originally designed for 3d models that were intended to be rendered out or rigged for animation offer way too many tools and options for the novice not specifically interested in those features. Can it draw what you want, and can it output a file suitable for printing? Those are the only two questions I needed answering when I went looking. All that said, whatever program you chose, Shapeways now offers a model check service that will let you know what parts will or won't work for your chosen material. Typically wall thickness and wire size are two of the biggies.
Teach yourself to model in an organized way, and one that produces "watertight" objects, and your problems with 3D printing will be far less when you get around to it.