I think it's pretty appropriate. First Avengers film establishes Thanos' existence, GotG establishes his name and his intentions, than this film shows that he's not going to sit around and rely on his many failed subordinates to get the job done. Frankly, it's about time. After GotG, Thanos came off as just a big head who could care less about what goes on in the universe. There's nothing really intimidating about him if you can bad talk his character, his daughters and kill his loyal subordinate all in one sitting and only a "don't mess with me" in response. Also, everyone turns on him in the end like it was something they've always wanted to do. Kingpin from the new Daredevil series not only commands respect and loyalty from his followers, he will go to your home and strangle you with his bare hands for just talking to his mother! I'd be more scared of Kingpin having the gauntlet than Thanos at this point.