This project sounds fun, how are you going to tackle Spider-man swinging around New York? I think you have two option available to you which are either a fully rigged 3D model with animation applied of the easier option would be green screen and then composite into shot.
I suspect the 3D option will be difficult to get right as even in the first Spider-Man his movements sometimes lacked realistic movements with regards to gravity, often seeming to float around in my opinion.
For the opening I would tone down the lens flares as to be honest it just screams "video copilot optical flares", I understand that they can give a more anamorphic look to the movie but everyone is doing the "JJ Abrams" thing now.
If you need a hand with anything let me know, I have multiple systems here complete with the following software:-
After Effects
BouJou
Cinema 4D
Premier Pro
Avid
Natural Motion
PFTrack
To name just a few.
All the best.