I airbrushed a custom paintball marker. Some parts were painted with lacquer, some with cheap Testors enamel and some areas were painted with Humbrols with a brush out of the can and some Humbrols were airbrushed.
I clear coated it with Krylon satin just fine, but I did very light coats. I would also let the Humbrols dry for 7-10 days. I spoke to a Humbrol distributor and they changed their formulations a couple years ago to meet environmental standards. This changed some colors, the consistency and drying and cure times.
If in doubt, do a test on scrap plastic etc. But it worked fine for me.