The thing that's going to make this kind of rough is the size. You'll need supplies that are bigger than anything you can get off-the-shelf at Michaels. I frame a lot of my own drawings and paintings, but 36 x 48 is larger than anything I've ever done.
By far, the worst part is going to be the mounting. It looks like that giclee is on paper, so it's going to need to be mounted to something like foamcore so that it can set in its frame. If you don't have a lot of experience with this sort of thing, then I really, really recommend
NOT doing it yourself. You might be able to find self-adhesive board in that size, but I'm not aware of anyone who makes it that big. If you can't find self-adhesive board, then you'd have to get regular foamcore and a suitable glue. Either way - if you're freaked at the combination of you, glue, and your print in the same room, then have a pro mount it. You need the right supplies; you need good lighting; you need a helper; and you need enough room to work. Otherwise, it can get tense.
The good news is that you
can find ready-made frames in 36x48. You may be able to do that locally, but you can do some online research at a place like ornateframes.com. Freight is going to be an added expense if you have to order something, but try pricing it out. If you're hoping to stay true to the set-used piece, keep in mind that you should match the moulding first. You can always replicate the finish later.
Assuming the print is on paper, you can use glass or not. It's canvas works that are generally not placed behind glass, in order to let the fibers breathe.
While this project isn't quite as easy as framing a fuzzy kitten poster from Target, you are dealing with a fairly standard size in the art world. This doesn't have to be a total custom job if you don't want it to be.
