I am serious about building one studio-scale eventually. I already made complete patterns for the NX-2000 for my friend Jim Creveling who got as far as building the primary hull in studio scale. Those were based on photos, now I can get it much more accurate so I will be going back and redoing them in CG in the very near future. Plan to do some experiments with CNC machining so it doesn't have to be hand sculpted and can be near perfect.
The challenge is all those viewports. I see only two options for big starship hulls, one being translucent fiberglass and the other vacu-formed clear butyrate. Having to cut out all the viewports is an unacceptable amount of work at least to me and makes it near impossible to get them all done right when viewed close up. The Excelsior has a lot of small windows in the secondary hull. For a model that needs to look good up close, being able to mask off and paint around those windows seems like the best approach?
REL, you are a talented sculptor. I'm sure that if you tackle this it will look awesome. At 1/350 52" sounds about right, just base it off an even 1500 foot length versus 1000 feet for the TMP Enterprise and you should have it. But, with something this big, it's going to be fiberglass, right? Can you do semi-clear castings? And how will that look if you mask off the viewports and paint over them? Or do you plan to cut them all out?