LoL. I'm not saying Wolverine (or at least Jackman's Wolverine) isn't a leftie. Just that his watch isn't conclusive evidence. Now, whatever hand he uses to hold his stogie ... THAT would be more compelling.
You guys mentioned Brisco County but left out Bruce Campbell's other famous characters.
Ash Williams of course becomes a lefty when he chops his right hand off. The rest of his characters, notably Bubba-Ho-Tep and Jack Stiles (Jack of All Trades).
Let's not forget my favourite of Bruce's roles, the Surgeon General of Beverly Hills in Escape from L.A.
I found this thread looking for info on left-handed rapiers, I know this is a necro but being a lefty I noticed that Harpo Marx and Kojak are not on the list