Of course they can, if they want to. Like changing the sex of a predator in the already made movies wouldn't actually make a difference at all, except for different junk between the legs which really isn't important for the storyline... It's still an antagonist who will hunt and kill people, which a female can do. Or like Wolf clean up a mess, which a female can do. Or like Scar, Dachande and Ahab -
help the main character, which a female can also do. Literally nothing would change except for maybe the pred's appearance. I'd
love to see a female pred as long as they don't make her to a skinny supermodel with huge boobs, like that concept for Predators which screamed sexism to me
"she will be more ninja like and sneaky
because female" like wow no excuse me while I go and vomit????
Like nah bro. Give me a female pred as described in that AvP novel. Make her huge and badass and super scary and hella strong. They're aliens. Be creative with the race and the culture, don't stick to human stereotypes with patriarchy and crap because they suck and are boring.
I've ranted quite a lot about this before on my tumblr blog and I just worldbuild about the Predator culture since the canon is broken anyway lmao. The writers can hire me, I can make it work!!