Let's see... You made it to where they've escaped the Kyln, and have made it to Knowhere and the Collector... I do think there's stuff in there that would have pulled you in more if you knew the comics. Not necessarily, but maybe. My friends I saw it with know those comics not at all, and enjoyed it. I just appreciated it on a different level because I know who Thanos is, and what the Infinity Stones mean, and was chuffed beyond description at the shot in the Collector's history of the Stones of the Celestial wielding the Power Stone:
That brief shot made me internally squee, because I know who they are and what they can do.
I'm assuming you've watched the other Marvel Cinematic Universe films to this point? Enough to get that the Tesseract from the first Captain America Movie was what was sketched in Howard Stark's notebook in Iron Man 2 -- and what Tony synthesized to power his new reactor, and that it is the Space Infinity Stone, and that the scepter Thanos gave Loki in the Avengers and that is now in the hands of Hydra is the Mind Infinity Stone, and that the Darkness from Thor: The Dark World is the Reality Infinity Stone...?
That's kinda the point of this film, to me. Peter, especially, is in the role of The Fool -- the adventurer blithely blundering forward and trusting to luck and his own abilities to see him through trials he has no way of imagining. The Nova Corps has been around for millennia. Thanos has been around for eons. The Infinity Stones are the most powerful relics known on several planes and date to the beginning of the universe. And this movie is about this little group of misfits coming together and giving all those cosmic entities the middle finger, even after beginning to have some sense of how out of their depth they are. And now we have four of the six Infinity Stones accounted for and the stakes go up from here. The last two Stones are Time and Soul, and we're not really sure where those are going to pop up or how.
So you may be one of those who would derive more from this movie, at least, if you had more of a sense of who and what you were seeing. I know it's supposed to be the role of the film-makers to get that across, but this is basically an Avengers, without the five lead-up films to get you acquainted with what's going on in the setting and who these people are.
--Jonah

That brief shot made me internally squee, because I know who they are and what they can do.
I'm assuming you've watched the other Marvel Cinematic Universe films to this point? Enough to get that the Tesseract from the first Captain America Movie was what was sketched in Howard Stark's notebook in Iron Man 2 -- and what Tony synthesized to power his new reactor, and that it is the Space Infinity Stone, and that the scepter Thanos gave Loki in the Avengers and that is now in the hands of Hydra is the Mind Infinity Stone, and that the Darkness from Thor: The Dark World is the Reality Infinity Stone...?
That's kinda the point of this film, to me. Peter, especially, is in the role of The Fool -- the adventurer blithely blundering forward and trusting to luck and his own abilities to see him through trials he has no way of imagining. The Nova Corps has been around for millennia. Thanos has been around for eons. The Infinity Stones are the most powerful relics known on several planes and date to the beginning of the universe. And this movie is about this little group of misfits coming together and giving all those cosmic entities the middle finger, even after beginning to have some sense of how out of their depth they are. And now we have four of the six Infinity Stones accounted for and the stakes go up from here. The last two Stones are Time and Soul, and we're not really sure where those are going to pop up or how.
So you may be one of those who would derive more from this movie, at least, if you had more of a sense of who and what you were seeing. I know it's supposed to be the role of the film-makers to get that across, but this is basically an Avengers, without the five lead-up films to get you acquainted with what's going on in the setting and who these people are.
--Jonah