If this is flexible ABS or HIPS that you want to fill, then the best result will be acquired with real ABS dissolved in acetone or "polystyrene cement" (the liquid kind). Dissolved ABS is easier to work with than dissolved HIPS. Dissolving it in poly cement is better than dissolving in acetone, but more expensive and is best for the final layer.
Apply in layers, and let dry before each new layer. Be careful to store it in an airtight jar because it evaporates quickly. It warps easily if you apply it too thick.
Not be easiest method by far, but the best final result.
I prefer epoxy over polyester resin, polyester resin being the stuff in Bondo. Epoxy has better adhesion and therefore it cracks less easy. Therefore, I suggest epoxy putty over Bondo.